This website is intended for residents of the United States of America interested in Phenylketonuria, also called PKU

Managing PKU

You can protect your brain by monitoring your diet and managing your PKU

Lifelong management of PKU may be difficult, but it is important to do in order to protect your brain. That’s because toxic buildup of phenylalanine (Phe) in the brain can cause physical changes that lead to intellectual and behavioral problems.

Although some symptoms are permanent, many can be improved if blood Phe levels come back under control.

You may have heard something different in the past, but experts now agree that PKU must be managed for life.

Start PKU management early. PKU should be managed from birth with all available options to control blood Phe levels.
Manage PKU for life. PKU is a lifelong condition that requires lifelong care.

The impact of high or unstable blood Phe levels can be managed, and in some cases, symptoms can be improved.

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Talk to a doctor about the current PKU treatment options.

Learn more about options

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Start monitoring your blood Phe levels.

Download and try using this Phe Tracking Guide

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Blood Phe Spot Tutorial

See the tutorial


Visit a PKU clinic and talk to a care team.

Use the Clinic Finder to connect with a care team near you

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Have an honest discussion with your care team.

Try this PKU Clinic Discussion Guide to help your conversation along

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Develop a routine that makes PKU management part of your day.

See how other people create healthy habits


Find a PKU clinic near you today.


Check out these delicious low-Phe recipes.